Items where Author is "McHale, Noel G."

Roy, Subhrangsu and Morayo Akande, Adebola and Large, Roddy J. and Webb, Tim I. and Camarasu, Costin and Sergeant, Gerard P. and McHale, Noel G. and Thornbury, Keith D. and Hollywood, Mark A. (2012) Structure-Activity Relationships of a Novel Group of Large-Conductance Ca(2+) -Activated K(+) (BK) Channel Modulators: The GoSlo-SR Family. ChemMedChem. ISSN 1860-7187 (In Press)

Kyle, Barry and Bradley, Eamonn and Ohya, S and Sergeant, Gerard P. and McHale, Noel G. and Thornbury, Keith D. and Hollywood, Mark A. (2011) Contribution of K v 2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra. Am J Physiol Cell Physiol.. (Submitted)

Thornbury, Keith D. and Hollywood, Mark A. and McHale, Noel G. and Sergeant, Gerard P. (2011) Cajal beyond the gut : interstitial cells in the urinary system – towards general regulatory mechanisms of smooth muscle contractility ? Acta gastro enterol. belg.,. , 74. pp. 536-542.

Walsh, Michael P. and Thornbury, Keith D. and Cole, William C. and Sergeant, Gerard P. and Hollywood, Mark A. and McHale, Noel G. (2011) The involvement of Rho-associated kinase in rabbit urethral smooth muscle contraction. Am J Physiol. , 300 (1). F73-85.

Large, Roddy J. and Hollywood, Mark A. and Sergeant, Gerard P. and Thornbury, Keith D. and Bourke, S. and Levick, J.R. and McHale, Noel G. (2010) Ionic currents in intimal cultured synoviocytes from the rabbit. Am J Physiol Cell Physiol, 299 (5). pp. 1180-1194.

Walsh, Michael P. and Thornbury, Keith D. and Cole, William C. and Sergeant, Gerard P. and Hollywood, Mark A. and McHale, Noel G. (2010) Rho-associated kinase plays a role in rabbit urethral smooth muscle contraction, but not via enhanced myosin light chain phosphorylation. Am J Physiol Renal Physiol . (In Press)

Bradley, Eamonn and Kadima, Sonia and Drumm, Bernard and Hollywood, Mark A. and Thornbury, Keith D. and McHale, Noel G. and Sergeant, Gerard P. (2010) Novel Excitatory Effects of Adenosine Triphosphate on Contractile and Pacemaker Activity in Rabbit Urethral Smooth Muscle. The Journal of Urology, 183. pp. 801-811. ISSN 0022-5347/10/1832-0801/0

Hollywood, Mark A. and Sergeant, Gerard P. and Thornbury, Keith D. and McHale, Noel G. (2010) The PI-PLC inhibitor U-73122 is a potent inhibitor of the SERCA pump in smooth muscle. Br J Pharmacol., 160 (6). pp. 1293-1294.

Sergeant, Gerard P. and Bradley, Eamonn and McHale, Noel G. and Hollywood, Mark A. (2008) Role of mitochondria in modulation of spontaneous Ca2+ waves in freshly dispersed interstitial cells of Cajal from the rabbit urethra. Journal of Physiology, 586 (19). pp. 4631-4642.

Beckett, E.A.H. and Hollywood, Mark A. and Thornbury, Keith D. and McHale, Noel G. (2007) Spontaneous Electrical Activity in Sheep: Mesenteric Lymphatics. Lymphatic Research and Biology, 5 (1). pp. 29-43. ISSN 1539-6851

McHale, Noel G. and Hollywood, Mark A. and Sergeant, Gerard P. and Shafei, M. and Thornbury, Keith D. and Ward, S.M. (2006) Organization and function of ICC in the urinary tract. JPhiosol, 576 (3). pp. 689-694. ISSN J Physiol. 2006 Nov 1;576(Pt 3):689-94.

Sergeant, Gerard P. and Johnston, Louise and McHale, Noel G. and Hollywood, Mark A. (2006) Activation of the cGMP/PKG pathway inhibits electrical activity in rabbit urethral interstitial cells of Cajal by reducing the spatial spread of Ca 2+ waves. Journal of Physiology, 574 (1). pp. 167-181.

Sergeant, Gerard P. and Hollywood, Mark A. and McHale, Noel G. (2006) Ca 2+ signalling in urethral interstitial cells of Cajal. Journal of Physiology, 576 (3). pp. 715-720.

Bradley, Eamonn and Hollywood, Mark A. and Johnston, Louise and Large, Roddy J. and Matsuda, T and Baba, A. and McHale, Noel G. and Thornbury, Keith D. and Sergeant, Gerard P. (2006) Contribution of reverse Na + –Ca 2+ exchange to spontaneous activity in interstitial cells of Cajal in the rabbit urethra. The Journal of Physiology, 574 (3). pp. 651-661.

Bradley, Eamonn and Hollywood, Mark A. and McHale, Noel G. and Thornbury, Keith D. and Sergeant, Gerard P. (2005) Pacemaker activity in urethral interstitial cells is not dependent on capacitative calcium entry. Am J Physiol Cell Physiol., 289 (3). pp. 625-632.

Johnston, Louise and Sergeant, Gerard P. and Hollywood, Mark A. and McHale, Noel G. (2005) Calcium oscillations in interstitial cells of the rabbit urethra. J Physiol, 565 (2). pp. 449-461.

Bradley, Eamonn and Anderson, U.A. and Woolsey, Siobhan M. and Thornbury, Keith D. and McHale, Noel G. and Hollywood, Mark A. (2004) Characterization of T-type calcium current and its contribution to electrical activity in rabbit urethra. Am J Physiol Cell Physiol., 286 (5). pp. 1078-1088.

Craven, M. and Sergeant, Gerard P. and Hollywood, Mark A. and McHale, Noel G. and Thornbury, Keith D. (2004) Modulation of spontaneous Ca2+-activated Cl- currents in the rabbit corpus cavernosum by the nitric oxide-cGMP pathway. J Physiol. , 556 (2). pp. 495-506.

Hollywood, Mark A. and Sergeant, Gerard P. and McHale, Noel G. and Thornbury, Keith D. (2003) Activation of Ca2+-activated Cl- current by depolarizing steps in rabbit urethral interstitial cells. Am J Physiol Cell Physiol. , 285 (2). pp. 327-333.

Hollywood, Mark A. and Woolsey, Siobhan M. and Walsh, I.K. and Keane, P.F. and McHale, Noel G. and Thornbury, Keith D. (2003) T- and L-type Ca 2+ currents in freshly dispersed smooth muscle cells from the human proximal urethra. J Physiol, 550 (3). pp. 753-764.

Sergeant, Gerard P. and Thornbury, Keith D. and McHale, Noel G. and Hollywood, Mark A. (2002) Characterization of norepinephrine-evoked inward currents in interstitial cells isolated from the rabbit urethra. Am J Physiol Cell Physiol., 283 (3). pp. 885-894.

Sergeant, Gerard P. and Hollywood, Mark A. and McCloskey, K. D. and McHale, Noel G. and Thornbury, Keith D. (2001) Role of IP(3) in modulation of spontaneous activity in pacemaker cells of rabbit urethra. Am J Physiol Cell Physiol., 280 (5). pp. 1349-1356.

Toland, H. M. and McCloskey, K. D. and Thornbury, Keith D. and McHale, Noel G. and Hollywood, Mark A. (2000) Ca(2+)-activated Cl(-) current in sheep lymphatic smooth muscle. Am J Physiol Cell Physiol., 279 (5). pp. 1327-1335.

Hollywood, Mark A. and McCloskey, K. D. and McHale, Noel G. and Thornbury, Keith D. (2000) Characterization of outward K(+) currents in isolated smooth muscle cells from sheep urethra. Am J Physiol Cell Physiol. , 279 (2). pp. 420-428.

Sergeant, Gerard P. and Hollywood, Mark A. and McCloskey, K. D. and McHale, Noel G. (2000) Specialised pacemaking cells in the rabbit urethra. J Physiol., 526 (2). pp. 359-366.

McCloskey, K. D. and Toland, H. M. and Hollywood, Mark A. and Thornbury, Keith D. and McHale, Noel G. (1999) Hyperpolarisation-activated inward current in isolated sheep mesenteric lymphatic smooth muscle. J Physiol. , 521 (1). pp. 201-211.

Cotton, K. D. and Hollywood, Mark A. and McHale, Noel G. and Thornbury, Keith D. (1997) Ca2+ current and Ca(2+)-activated chloride current in isolated smooth muscle cells of the sheep urethra. J Physiol. , 505 (1). pp. 121-131.

Cotton, K. D. and Hollywood, Mark A. and McHale, Noel G. and Thornbury, Keith D. (1997) Outward currents in smooth muscle cells isolated from sheep mesenteric lymphatics. J Physiol. , 503 (1). pp. 1-11.

Hollywood, Mark A. and Cotton, K. D. and Thornbury, Keith D. and McHale, Noel G. (1997) Tetrodotoxin-sensitive sodium current in sheep lymphatic smooth muscle. J Physiol. , 503 (1). pp. 13-20.

Hollywood, Mark A. and McHale, Noel G. (1994) Mediation of excitatory neurotransmission by the release of ATP and noradrenaline in sheep mesenteric lymphatic vessels. J Physiol. , 481 (2). pp. 415-423.

Thornbury, Keith D. and Hollywood, Mark A. and McHale, Noel G. (1992) Mediation by nitric oxide of neurogenic relaxation of the urinary bladder neck muscle in sheep. J Physiol. , 451. pp. 133-144.